Clarksville is a city in and the county seat of Montgomery County, Tennessee, United States, and the fifth largest city in the state. The population was 132,929 in 2010 United States Census. Clarksville is the principal central city of the Clarksville, TN-KY metropolitan statistical area, which consists of Montgomery County, Stewart County, Tennessee, Christian County, Kentucky and Trigg County, Kentucky.

The city was incorporated in 1785, and named for General George Rogers Clark, frontier fighter and Revolutionary War hero, brother of William Clark of the Lewis and Clark Expedition.